Patrick and Daniel ConwayOwners, Great Lakes Brewing Co., Cleveland Age: Pat, 47; Dan, 34. Why they are rising: Great Lakes, which opened in 1988, put these brothers in the vanguard of America's beer renaissance. Their beers, 30 different styles that change with the seasons, have won dozens of gold medals in the World Beer Championships and the Great American Beer Festival. Have unusually good food for a brew pub concept, and a menu that matches beer with food. Have had their beers featured ...

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